Associate Laboratory Director Northwestern University Chicago, Illinois, Illinois
The advancement of molecular HLA typing technologies, along with computational methods for analyzing B-cell and T-cell HLA determinants/targets (often referred to as "epitopes"), has led to the development of tools for assessing the degree of donor-recipient HLA disparity at the molecular level. This session will provide a historical overview of molecular HLA mismatch analysis, explore the various available tools, address their limitations, and critically evaluate the current clinical evidence regarding the use of these tools in transplant practices.