Abstract I: From Haplotypes to Antibodies: Bioinformatics tools in basic and translational immunogenetics

Speaker(s)

• 

  Ahmed Mostafa, MD, PhD, F(ACHI)

  Director, Technical Supervisor, and Clinical Consultant
  University of Saskatchwean
  Saskatoon, SK, Canada
• 

  Yan Li, PhD, F(ACHI) (he/him/his)

  Assistant Director of Histocompatibility Lab
  Beth Israel Deaconess Medical Center
  Boston, MA
• 

  Yang Li, M.B.

  Histocompatibility Specialist
  The First Affiliated Hospital of Soochow University
  Suzhou, Jiangsu, China (People's Republic)
• 

  Nicholas Pollock, PhD candidate (he/him/his)

  Pre Doctoral
  University of Colorado AMC
  Lochbuie, Colorado
• 

  Mitchell Ellison, PhD

  Bioinformatics Scientist
  UPMC
  Gibsonia, PA
• 

  Busra Coskun

  Undergraduate Student
  University of Pennsylvania
  Philadelphia, PA

Moderator(s)

• 

  Danillo Augusto, PhD

  Assistant Professor
  UNC Charlotte
  Charlotte, NC
• 

  Abeer Madbouly, PhD

  Consultant
  MHC Therapeutics Bioconsulting
  Minneapolis, MN

Presentations:

• 2:45 PM - 3:00 PM US EDT

  Triple Algorithm-Based Prediction of De Novo Donor-Specific Antibody Formation in Kidney Transplant Recipients
  

  Speaker: Ahmed Mostafa, MD, PhD, F(ACHI) – University of Saskatchwean
• 3:00 PM - 3:15 PM US EDT

  Correlate the flow crossmatch results with the single antigen results using logistic regression
  

  Speaker: Yan Li, PhD, F(ACHI) (he/him/his) – Beth Israel Deaconess Medical Center
• 3:15 PM - 3:30 PM US EDT

  Optimizing HLA Prediction via EM-Filtered Near-True and Family-Derived True Haplotypes for Precision Donor Matching in Transplantation
  

  Speaker: Yang Li, M.B. – The First Affiliated Hospital of Soochow University
• 3:30 PM - 3:45 PM US EDT

  Creating Fully Representative MHC Reference Haplotypes
  

  Speaker: Nicholas Pollock, PhD candidate (he/him/his) – University of Colorado AMC
• 3:45 PM - 4:00 PM US EDT

  Addition of HLA-DQA1/DQB1 trans heterodimers to single-molecule eplet mismatch analysis does not improve risk stratification for DSA, AMR, or Graft Loss
  

  Speaker: Mitchell Ellison, PhD – UPMC
• 4:00 PM - 4:15 PM US EDT

  immunogenetr: a comprehensive toolkit for clinical HLA informatics
  

  Speaker: Busra Coskun – University of Pennsylvania